While iTunes makes it easy to download album artwork and transfer it to your iPod, removing the artwork is a different story. There is no option to automatically remove all album artwork from iTunes. However, you can remove it from individual songs or albums. This is useful if iTunes downloaded the incorrect album artwork: after clearing it, you can replace it with the correct artwork. You can also clear album artwork to save space on your iPod.
Instructions
Clear Artwork from an Album
1. Open iTunes and select "Music" in your Library.
2. Select all of the songs from same album. You can either hold "Ctrl" and click each song in the album, or select the first song in the album, press and hold the "Shift" key and click the last song in the album.
3. Right-click on the selected album. Select "Clear Downloaded Artwork" from the context menu. Click the "Clear Downloaded Artwork" button in the confirmation window that opens.
Clear Artwork from Individual Songs
4. Open your iTunes music library. Right-click a song.
5. Select "Get Info" from the context menu. Click the "Artwork" tab to show the album art.
6. Click the album artwork, then click the "Delete" button to remove the artwork from the song file.